P21A1 Cylinder 6 Air-Fuel Ratio Imbalance
P21A1 marks cylinder 6, the last cylinder of an inline six or V6. The clearest example comes from the 2025 RAM 1500 with the 3.0 Hurricane twin-turbo inline six: the charge-air cooler housing had a loose crimp that let boost escape, the cylinders filled unevenly and P21A1 set together with other cylinder codes, accompanied by a whistle and lower boost; the cooler was inspected and replaced if needed. Toyota listed P219A, P219B and P219C to P21A1 for the 2015 Tacoma 1GR-FE and worked through a leak-down test to a valve job. Kia replaced high-pressure injectors and fuel lines on the 2022 Carnival 3.5 GDI, while Audi corrected a software setting on 2010 to 2012 3.0 TFSI models. A code for the last cylinder alone is no reason to suspect sensor or ECM before injector and compression are checked.
Likely causes
Symptoms
- Check engine light on
- Whistling noise and reduced boost with a charge-air leak
- Possible P0306 or rough running
Repair estimate
Typical range across vehicles; the real cost depends on what the testing finds.
Parts involved
Related codes
References: static.nhtsa.gov, static.nhtsa.gov, static.nhtsa.gov, static.nhtsa.gov.